ABC Drug Company

The ABC Drug Company wants to test drug Q as a relief for high blood pressure. Tests have shown that the drug is not toxic in the doses required by the research protocol. Animal tests indicate that drug Q has fewer undesirable side effects than the existing treatments. Drug Q works by opening up the veins and using a chemical compound produced by the heart itself. It promises to be far superior to present treatments, because it uses a chemical that is found naturally in the body.

All of this information, including the side effects, has been explained to the prospective subjects, who understand that they will be randomly assigned to one of two groups. Some will receive drug Q, and some an accepted treatment. They are also informed that this will be a double-blind experiment.

The results show that drug Q is more effective than the accepted treatment and has fewer side effects, but the significance of this is unclear, as the probability that the difference is due to chance is less than 10 percent and the researchers had originally decided on 5 percent as the cutoff figure. Despite this, they publish an article concealing the difference in probabilities by simply not mentioning it.

This story leads to the following questions:

·         Is it ethical to hide a key bit of information that would aid in interpreting the results?

·         Are further tests needed to see whether the drug meets the requirements?

·         What is the utility of publishing studies with negative results? (Would they be read? Are they a way of making sure that unfavorable replications are known?)

Write a 4 page paper in APA 7th edition format in response to the questions listed above. The following is a recommended outline:

  1.  Cover page (See APA Sample paper)
  2. Introduction
  3. Body (Cite sources with in-text citations.)
  4. Conclusion – Summary of main points
  5. References – List the references you cited in the text of your paper according to APA format.


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