Ulcerative Colitis

Respond to your colleagues, in one or more of the following ways:

  • Share insights on how the factor you selected impacts the pathophysiology of the disorder your colleague selected.
  • Suggest alternative recommendations for drug treatments.
  • Expand on your colleague’s posting by providing additional insights or contrasting perspectives based on readings and evidence.

  A brief description of the pathophysiology of Ulcerative Colitis

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                  Ulcerative Colitis is a chronic inflammatory bowel disease wherein the immune system attacks and causes inflammation on the inner lining of the large intestine. This is a disorder that may occur at any age but is common among young people ages 20 to 40 (McCance & Huether, 2019). Common signs and symptoms include diarrhea, passing of bloody stool and abdominal pain. Factors that greatly affect UC are genetics, over reactive immune response, microbiome and the environment.  

       Explain how the maladaptive and physiological responses of Ulcerative Colitis might differ.

        The physiological responses to this disease vary from one person to another. There is mild to moderate UC and every person may differ on how they can live and deal with the disease. For those whose coping mechanism is healthy, going to the doctor for treatment and looking for means to live with the disease without significant disruption is their primary management of living with UC. Eating healthy is one of the ways to deal with the disease as one’s appetite can be greatly affected and one may easily lose weight or eat an unbalanced diet (NIH, n.d.). Looking for a support group is also one of the ways by which a person may cope with UC, knowing that he or she is not alone in her condition.

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        Maladaptive response is to isolate one’s self as a result of fear of embarrassment, depression and anxiety caused by the disease. This is all due to the nature of the disorder that hampers normal way of living and as a young adult who is seeking the company of friends, the person living with UC becomes self-conscious as accidents from diarrhea may occur at any time ( Phillips, 2019).

       The most common drug, used by 90% of people with UC is 5-ASA. Under the classification of this drug are Sulfasalazine and Mesalamine (BWH, n.d.). These two medications help by reducing the inflammation. Other drugs that may also use are immunomodulators and corticosteroids.

       The factor I have selected that may impact UC is age. As this disease may affect any age, the same hampering and psychological issues may crop up in the life of the person. Anyone not exactly living with UC understands how the uncertainty of having to pass gas or have diarrhea in a public place may send you in utter fear of being looked down or seen as filthy but would most especially affec t you around your friends.

 References :   

American Gastrointestinal Association. (2019). Clinical guidelines. Retrieved from https://www.gastro.org/guidelines

BWH. (n.d.). https://www.bwhcrohnscolitis.org/ibd-101/medications/5-asa/

Managing inflammatory bowel disease – full text view. (2015). https://clinicaltrials.gov/ct2/show/NCT00679003


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